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Dopamine D1 PAM Publication

December 1, 2020

The structure-activity relationship study on the pyrimidone series of dopamine D1 receptor positive allosteric modulators (PAMs) was just published in Bioorganic and Medicinal Chemistry Letters; many thanks to Prashi, Kadee and our collaborators in the Sibley Lab for all their … Read more

New publication on HCV anti virals

September 2, 2020

We are excited to share the initial preclinical results on our anti-HCV lead compound, fluoxazolevir, in Nature Microbiology. Many thanks to our collaborators who made this possible!

Welcome, Amber and David!

August 19, 2020

We are excited to welcome two new post-doctoral scholars to the team, Amber Kelley and David Rogers. Amber joins us from the Petersen Lab at UNC, Greensboro to work on the dopamine modulators project. David joins us from the Lamar … Read more

New publication on D3 dopamine agonists

May 14, 2020

We are excited to see our long-standing collaboration with the Sibley Lab at NINDS to develop selective D3 dopamine receptor agonists published in The Journal of Medicinal Chemistry. Congratulations to all the many contributors to this project!

Congratulations, Disha!

April 27, 2020

Disha has started her new position as medicinal chemist at Neurocrine Biosciences. We will miss her here and wish her all the best on the West Coast!